BMJ Best Practice Podcast

Type 1 diabetes

Type 1 diabetes mellitus is a metabolic disorder characterised by hyperglycaemia due to absolute insulin deficiency. The condition develops due to destruction of pancreatic beta cells, mostly by immune-mediated mechanisms.
In this podcast, Rajesh Garg, Professor of Medicine, University of Miami Miller School of Medicine, gives us an overview of the condition.
For more on type 1 diabetes, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/25
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The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Generalised anxiety disorder

Generalised anxiety disorder (GAD) is a common condition defined as chronic, excessive worry for at least six months that causes distress or impairment.
Christopher Gale, Research Director and Consultant Psychiatrist, Southern District Health Board, New Zealand gives a clinical overview of the condition.
For more on GAD, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/120
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The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Lyme disease

Lyme disease is an infectious disease transmitted to humans through the bite of infected ticks.
Erythema migrans develops at the site of tick bite usually within 1 to 2 weeks and is a pathognomic feature. Constitutional symptoms such as fever, headache, myalgias, fatigue, and arthralgias may occur.
In this podcast, Janak Koirala, Professor of Medicine and Infectious Diseases, Division of Infectious Diseases, Southern Illinois University School of Medicine, gives us an overview of the condition.
For more on lyme disease, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/224
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The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Jet lag

Jet lag and sleep phase disorders affect millions of travellers worldwide. Rapid change in time zone produces a constellation of symptoms called jet lag disorder.
Symptoms include difficulty initiating and maintaining sleep, reduced daytime alertness, general malaise, and gastrointestinal symptoms.
In this podcast, Ashish Adlakha, Assistant Clinical Professor, Neurology and Sleep Medicine, Connecticut Healthcare, gives us a clinical overview.
For more on jet lag, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/1017
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The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Post-traumatic stress disorder

Post-traumatic stress disorder may develop (either immediately or delayed) following exposure to a stressful event or situation of an exceptionally threatening or catastrophic nature.
According to DSM-5, it is characterised by 4 groups of symptoms: intrusion symptoms, avoidance, negative alterations in cognition and mood, and alterations in arousal and reactivity. These symptoms must impair function for a diagnosis to be made.
In this podcast, Mathew Hoskins, Consultant Psychiatrist and Clinical Teaching Fellow, Cardiff University, gives us a clinical overview of the disorder.
For more on PTSD, visit BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/430
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The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Chronic congestive heart failure

Chronic congestive heart failure is a complex clinical syndrome that can result from any structural or functional cardiac disorder that impairs the ability of the ventricle to fill with or eject blood.
It is a major and growing public health problem.
In this podcast, Syed Wamique Yusuf, FACC, FRCPI
Syed Wamique Yusuf, Professor of Medicine, Department of Cardiology, University of Texas MD Anderson Cancer Center, gives a clinical overview of the condition.
For more on chronic congestive heart failure, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/61
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The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

COVID-19: Vaccine immunogenicity, interleukin-6 inhibitors, mucormycosis

Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to Covid-19.
Abigail Davis, GP and section editor, covers the latest evidence around vaccine immunogenicity in different immunosuppressed populations, as well as the use of interleukin-6 inhibitors in COVID-19 patients.
And Emma Scott, section editor, updates us on mucormycosis, or black fungus infection in COVID-19 patients.
For more, see:
BMJ Best Practice's topic on COVID-19: bestpractice.bmj.com/topics/en-gb/3000168
BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): new-learning.bmj.com/course/10065100
BMJ Learning COVID-19 in primary care module: new-learning.bmj.com/course/10065230
Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00676-0/fulltext
Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19: https://www.nejm.org/doi/full/10.1056/NEJMoa2100433
WHO Therapeutics and COVID-19: living guideline: https://app.magicapp.org/#/guideline/nBkO1E/section/LrV7OL
Indian Council of Medical Research advice on mucormycosis: https://www.icmr.gov.in/pdf/covid/techdoc/Mucormycosis_ADVISORY_FROM_ICMR_In_COVID19_time.pdf

Persistent depressive disorder

Persistent depressive disorder is a category that includes various forms of chronic depression in which depressive symptoms are present 'more days than not' over at least a 2-year period (1 year in children and adolescents).
David J. Hellerstein, Professor of Clinical Psychiatry, Columbia University Medical Center, gives us a clinical overview of the condition.
For more on persistent depressive disorder, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/805
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The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Chronic sinusitis

Chronic sinusitis is inflammation of the paranasal sinuses lasting more than 12 weeks.
Symptoms include facial pressure, rhinorrhoea, postnasal drainage, congestion, and general malaise.
Raj Sindwani, Section Head of Rhinology, Sinus, and Skull Base Surgery, Head and Neck Institute, Cleveland Clinic Foundation, gives us a clinical overview of the condition.
For more on chronic sinusitis, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/15
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The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Bulimia nervosa

Bulimia nervosa is an eating disorder, characterised by severe preoccupation about weight and body shape. Includes recurrent episodes of binge eating with compensatory mechanisms, such as self-induced vomiting, to prevent weight gain.
Debra Safer, Associate Professor, Co-Director of Stanford Eating and Weight Disorders Program, Stanford University School of Medicine, gives us an overview of the condition.
For more on bulimia nervosa, see BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/441
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The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.